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President Biden is banking on longtime bipartisan interest in eliminating cancer deaths to secure some of his most significant health spending increases for next year.

In a long-awaited 2024 budget proposal released Thursday, the president asked for a combined $3.6 billion over the next few years to be channeled to the Cancer Moonshot, a mission to end cancer that he first launched as vice president in 2016, less than a year after his son Beau’s death from brain cancer.

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The new Advanced Research Projects Agency for Health would also get a $1 billion increase to its budget, bumping it to $2.5 billion total. ARPA-H, launched last year with the sweeping mandate to tackle some of the nation’s biggest health care challenges like cancer and Alzheimer’s disease, is still in hiring mode.

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