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At the bustling Chicago O’Hare airport, my luggage and I collided with an elderly couple. My heart sank when I realized my vision had failed me again. Because of a connective tissue disorder, my peripheral vision and balance were impaired, making such unintentional mishaps part of my journey.

Moments like these are stark reminders of the day-to-day issues that patients with rare diseases often face. I know this not only from my own experience living with a genetic disorder, but also from treating many patients and researching gene therapies for more than two decades.

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Fortunately, my symptoms were largely alleviated when geneticists and doctors at the National Institutes of Health and the Baylor College of Medicine found a treatment that compensates for the mutated protein behind the disorder.

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